Information about Globulin

Globulin is one of three serum proteins found in the blood. The others are fibrinogen and albumin. Globulin is vital for the normal function of the human body and its tissues and organs. A surfeit of globulin can cause a wide range of serious health problems, while a shortfall of that same protein can be equally problematic but in different ways. When speaking of globulin, the term globular protein is sometimes used, but it should be noted that albumin is another form of globular protein, so it is important to understand that globulin and globular protein are not interchangeable terms.

The main purpose of globulin and the other serum proteins in the human body is to provide energy to the tissues, distribute proteins, as well as to fight infections. Globulin is also important in the process of blood clotting.

Globuli for test

When testing for the possibility of quite a large number of different diseases and disorders, establishing globulin levels is an important part of a doctor’s diagnosis. However, there are four different groups of globulin; these are alpha-1, alpha-2, beta, and gamma globulins, so the medic must identify which of these, if any, has abnormal levels, which in turn might point to an underlying problem. If a test finds abnormally high globulin levels, this could be an indicator of the following diseases: rheumatoid arthritis, leukaemia, various chronic inflammatory diseases (e.g. syphilis and tuberculosis), liver diseases such as cirrhosis and jaundice, ulcerative colitis, various autoimmune disorders, plus chronic viral and bacterial infections (e.g. hepatitis and HIV).

Globulin Levels

On the other hand, low globulin levels could ring a different set of alarm bells, being a possible indicator of things like celiac disease, irritable bowel syndrome, anaemia, and some kidney diseases.

There are different reasons why globulin levels may become raised, but it should be noted that meddling with things like anabolic steroids, preparations containing Human Growth Hormone (HGH), and progesterone may all have the effect of raising levels of globulin in the blood. It is also known that elevated levels of oestrogen and extended use of oral contraceptives may both have an impact on globulin levels.

If you have been feeling unwell for a while, it is always best to seek a consultation with a qualified medical practitioner rather than trusting to luck. You can bet that testing for globulin levels is one guaranteed way that the doctor can get to the bottom of what is ailing you and so you should set up a consultation as a matter of urgency.

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